WebMar 7, 2024 · Boronolectin based Near-IR fluorescent probe: a benzoboroxol-tricarbocyanine based probe with large Stokes shift, fluorogenic response and high selectivity for glycoproteins was developed.The performance of the dye was demonstrated in live epithelial cells by imaging mucin granules. It was possible to detect differences in … WebJun 15, 2015 · Two fluorescent diboronic acid compounds (6a and 6b) with a dipeptide linker were synthesized as potential sensors for cell surface saccharide Lewis X (Le X).Compound 6a with a dipeptide (H-Asp-Ala-) as the linker was found to selectively label CHOFUT4 cells, which express Le x, at micromolar concentrations, while non-Le x-expressing control …
Siming WANG Georgia State University, GA GSU Department …
WebDec 1, 2013 · Carbohydrate-based biomarkers such as sialyl Lewis X are known to correlate with cancer formation and progression. By targeting sialyl Lewis X, we have developed a boronolectin-fluorophore conjugate, which was able to selectively label and image xenograft (sc) tumor. This represents the very first example that a small molecule … WebNov 10, 2024 · We report a nontraditional therapy to combine three components in one macromolecular system, in which boronic acid adheres to peptidoglycan or … plated weight meaning
Trio Act of Boronolectin with Antibiotic-Metal Complexed …
WebSep 1, 2024 · Herein we report new work on grafting cobaltocenium-containing polymers from iron oxide nanoparticles using surface-initiated reversible addition-fragmentation chain transfer (SI-RAFT) polymerization (Scheme 1).In doing so, the magnetic properties of nanoparticles compliment the antimicrobial features of cobaltocenium-containing … WebFeb 12, 2015 · This work describes a novel mono-boronic acid derivative of a tricarbocyanine. The probe is a genuine near-infrared fluorescence emitter with improved properties such as a large Stokes shift, excellent water solubility and sensitive fluorogenicity upon binding to carbohydrates under physiological conditions. WebThis paper reports antimicrobial metallopolymers containing biodegradable polycaprolactone as the backbone with boronic acid and cobaltocenium as the side chain. While boronic acid promotes interactions with bacterial cells via boronolectin with lipopolysaccharides, cationic cobaltocenium facilitates the uni prickly heat suntan lotion