High affinity copper uptake protein

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August undefined, 2024

WebAlternate Antibody Name: Alternate Gene Names: Solute Carrier Family 31 (Copper Transporter), Member 1; COPT1; CTR1; Copper Transporter 1; Solute Carrier Family 31 … WebWe ascertain the ability of these proteins to functionally complement and transport copper in the corresponding Saccharomyces cerevisiae high-affinity copper transport mutant. The specific expression pattern of the Arabidopsis COPT1–5 mRNA in different tissues was analyzed by RT-PCR.

Nerve Growth Factor Peptides Bind Copper(II) with High Affinity: A ...

Web1 de abr. de 2024 · The CTR1 gene of Saccharomyces cerevisiae encodes a protein required for high affinity copper uptake. The protein is expressed on the plasma membrane, is heavily glycosylated with O-linkages, and ... WebCrystal structure of the high-affinity copper transporter Ctr1. PDB DOI: 10.2210/pdb6M97/pdb. Classification: TRANSPORT PROTEIN. Organism (s): Salmo salar, Escherichia coli. Expression System: Komagataella phaffii GS115. Mutation (s): Yes. Membrane Protein: Yes OPM PDBTM MemProtMD mpstruc. Deposited: 2024-08-22 … how many more months until april 2023

High affinity binding between copper and full-length prion protein ...

WebHigh affinity copper uptake protein 1 Gene SLC31A1 Status UniProtKB reviewed (Swiss-Prot) Organism Homo sapiens (Human) Amino acids 190 Protein existence Evidence at protein level Annotation score 5/5 Entry Feature viewer Publications External links History BLAST Download Add a publication Entry feedback Function WebCatalog FieldsAntigen: High affinity copper uptake protein 1Available to For-Profits: YesAntigen Species: HumanHybridoma Cells Available (Non-Profit): NoIsotype: MIgG2bDepositor: Clinical Proteomics Technologies for CancerHost Species: mouseAntigen Sequence: Positive Tested Species Reactivity: HumanDepositors Institution: National … Web15 de abr. de 2024 · High affinity copper uptake protein 1 (pig) Protein Target - PubChem Apologies, we are having some trouble retrieving data from our servers... how many more months until june 23

Identification of a copper transporter family in - Springer

SOLUTE CARRIER FAMILY 31 (COPPER TRANSPORTER), MEMBER 1; SLC31A1

High affinity copper uptake protein 1 (CTR1) is a protein that in humans is encoded by the SLC31A1 gene. Copper is an element essential for life, but excessive copper can be toxic or even lethal to the cell. Therefore, cells have developed sophisticated ways to maintain a critical copper balance, with the intake, export, … Ver mais In 2024, a new autosomal-recessive disease was discovered that is caused by mutations of the CTR1 gene. The disease is characterized by profound deficiency of copper in the central nervous system and presents with … Ver mais • Solute carrier family Ver mais • Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". … Ver mais Web8 de abr. de 2024 · HIGHLIGHTS. who: Nina Salustros from the (UNIVERSITY) have published the research: Structural basis of ion uptake in copper-transporting P1B-type ATPases, in the Journal: (JOURNAL) of 16/08/2024 what: Transport and regulation mechanism Based on detailed analyses of the structurally determined E1 state and … how big are harbor sealsWeb12 de out. de 2012 · The Ctr1 gene encodes a multispanning plasma membrane protein of 460 amino acids and is a necessary factor in high affinity copper uptake and supplies copper for all known copper-dependent physiological processes (Georgatsou et al., 1997, Sinani et al., 2007, Nakagawa et al., 2010). how many more months until christmas

"Webhigh-affinity copper uptake (17, 18). Based on its copper-transporting function in a yeast assay, its sequence similarity to the yeast high-affinity copper uptake protein, and its ubiquitous expression, we hypothesized that CTR1 is required for copper uptake in mammalian cells (4). Indeed two recent studies, involving 64Cu uptake (19) and ... " - High affinity copper uptake protein

High affinity copper uptake protein

SOLUTE CARRIER FAMILY 31 (COPPER TRANSPORTER), MEMBER 1; SLC31A1

WebBecause copper uptake at the cell membrane is a crucial step in copper acquisition, yeast genes encoding the high affinity copper transport proteins are tightly regulated in response to copper levels to ensure that … WebProtein target information for High affinity copper uptake protein 1 (Norway rat). Find diseases associated with this biological target and compounds tested against it in …

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Web5 de jan. de 2024 · high affinity copper uptake protein 1, copper transporter 1, solute carrier family 13 (sodium/sulphate symporters), member 1 GeneRIFs: Gene … Web27 de abr. de 2024 · In silico analysis has revealed three ferroxidase genes, namely CgFET3 (high affinity iron uptake; 70% similarity with ScFET3), ... Rydén, L.G.; Hunt, L.T. Evolution of protein complexity: The blue copper-containing oxidases and related proteins. J. Mol. Evol. 1993, 36, 41–66.

WebChimera protein of High affinity copper uptake protein 1 and Soluble cytochrome b562COPPER (I) IONZINC ION NCBI National Center forBiotechnology Information Search 6M98: Crystal structure of the high-affinity copper transporter Ctr1 in complex with Cu(I) Biological Unit for 6M98: trimeric; determined by author and by software (PISA) WebIt was shown that a gene, CTR1, encoded a multispanning plasma membrane protein that was specifically required for high affinity copper transport into yeast.The CTR1 gene product is a protein composed of 406 amino acid residues. A second high affinity copper uptake protein, encoded by the CTR3 gene, was subsequently identified. The two gene …

WebChimera protein of High affinity copper uptake protein 1 and Soluble cytochrome b562HEXATANTALUM DODECABROMIDEZINC ION. NCBI. National Center for Biotechnology Information. Search. 6M97: Crystal structure of the high-affinity copper transporter Ctr1. PDB ID: 6M97 Download: MMDB ID: 173912: PDB Deposition Date: WebGene ID: 102804936, updated on 5-Feb-2024. Summary Other designations. high affinity copper uptake protein 1-like

Web1 de out. de 2002 · High affinity copper uptake protein 1 Gene Slc31a1 Status UniProtKB reviewed (Swiss-Prot) Organism Mus musculus (Mouse) Amino acids 196 Protein …

Web16 de mar. de 2010 · Copper and iron are essential elements employed in pathways that are conserved in all kingdoms of life. In eukaryotes, several interdependent connections between copper and iron homeostasis have been described previously ().For example, high-affinity iron uptake in Saccharomyces cerevisiae is mediated by multicopper … how many more months until march 23WebThe major human high-affinity copper uptake protein, human copper transporter hCTR1, was recently shown to be at the basolateral or blood side of both intestinal and renal ... how big are herringsWeb30 de mar. de 2024 · Functional assays revealed that it stimulates the initial rate of radiolabeled copper uptake. CTR1 transports copper with high affinity in a time-dependent and saturable manner and is copper-specific. Transport is an energy-independent process and is stimulated by extracellular acidic pH and high K+ … how big are hershey barsWeb21 de mar. de 2024 · High Affinity Copper Uptake Protein 1 3 4 Copper Transporter 1 3 4 Solute Carrier Family 31 (Copper Transporters), Member 1 3 Copper Transport 1 Homolog 3 External Ids for SLC31A1 Gene HGNC: 11016 NCBI Entrez Gene: 1317 Ensembl: ENSG00000136868 OMIM®: 603085 UniProtKB/Swiss-Prot: O15431 Previous HGNC … how big are helmet stickersWeb15 de mar. de 1996 · Two proteins in the plasma membrane of yeast—a multicopper oxidase, encoded by the FET3 gene, and a permease, encoded by the FTR1 gene—were shown to mediate high-affinity iron uptake. FET3 expression was required for FTR1 protein to be transported to the plasma membrane. how big are hemorrhoidsWebHigh CTR1 Expression is associated with poor response to chemotherapy in Muscle-invasive Bladder Cancer. Gene silencing of either CTR1 or DMT1 did not affect copper … how big are heart stentsWeb30 de dez. de 2005 · High affinity copper binding by wild type PrP has been confirmed by the independent techniques indicating the presence of specific tight copper binding sites … how many more months until june 1st